"The Informer."

Zhang Jiahui and Nursery

Nursery "Talk about love and dance" Zhang Jiahui "Smell the fragrance and know the woman"

　　　　　　　 The 2010 most affectionate police and bandit blockbuster "Informer", jointly produced by Huayi Brothers, Emperor Film, and Yindu Organization, and jointly created by the original cast of the Golden Horse and the Academy Awards in 2009, was first exposed on August 2, allowing audiences to incarnate as "informants" and explore their own ultimate version of "Informer" from the "clues" of the stills.

Zhang Jiahui Nursery’s "Informer" Continues Its Front

　　　　　　　 The first exposure of the scene is the opposite play between the six-star actor Zhang Jiahui and the temperament actress Nursery. The two have a good relationship through "Witness", and they have joined hands for the second time in "Informant", and they are already emotionally familiar. Zhang Jiahui laughed and said that playing husband and wife for the second time is a delicate fate, and I am very happy to renew the relationship with her. Zhang Jiahui also praised the nursery’s acting skills as more mature than "Witness". "This time in" Informant ", the actors have more inner scenes, and everyone is burdened with different burdens. It is not easy to master the role, and it takes a lot of thought to understand. I can see that she is very hard-working, and she is willing to ask others humbly, and she is a very malleable actor."

　　　　　　　 The nursery also praised Zhang Jiahui’s dedication, "I really appreciate his professionalism and attitude, and I also regard him as my learning object." The two of them had such a tacit understanding, and the director was naturally reluctant to "let down" this relationship. He simply slowed down in the fast pace of the movie, and let the two of them talk about love through dance, express their feelings and passion with their bodies, and interlock their eyes and ten fingers tightly. The affectionate index is directly comparable to that of Hollywood classics. In that moment, the hurried time and space faded from irritability, in exchange for the beauty of silence.

Nursery "Talk about love and dance" Zhang Jiahui "Smell the fragrance and know the woman"

　　　　　　　 The humble Mr. Cheung laughs that he is "as stiff as a robot, remembering the dance steps in his mind but forgetting the dialogue. It is always difficult to connect the two things." He also feels sorry for his wife in the play, saying that he is "often half a beat slower, stepping on the instep of the nursery, causing her to have a big shoe print on her foot, which is really embarrassing." But the nursery clearly disagrees with him. She readily says that "Jiahui shouts hard on the surface, but in fact it does not affect his performance. When others are resting, he practices hard, and every detail is perfect." For her, she was also very happy to be able to use her dance expertise in "The Informer", and she liked this scene even more. "I like this scene the most in the movie, because the husband and wife dance in love, which is really romantic."

　　　　　　　 Although Zhang Jiahui claimed that the dance drama was sad and the action drama was sad, he still used his delicate acting skills to prove that the name of the best actor was not a lie. His gentle embrace, affectionate gaze, and complex emotions made Jiahui dance this dance vividly, and his personal style was like that of Al Pacino. However, he was still unwilling to be arrogant and showed the elegance of a gentleman’s atmosphere in silence, in line with the affectionate and righteous but implicit and low-key style of "The Informer".

　　　　　　　 Watch the stills of "The Informer" and create your own version of the ultimate "The Informer". On August 26, Hong Kong, mainland China, made a strong debut at the same time. The most emotional police and bandit blockbuster in the summer of 2010, emotional detonation, ready to go.

Zhang Xinghua

Cctv newsZhang Xinghua, born in 1988, is now the assistant to the squadron leader of the First Squadron of Dongchuan Brigade of Xining Public Security Fire Brigade. Since the police, he has been rated as an advanced individual in Yushu earthquake relief of the Fire Department of the Ministry of Public Security, and won the third-class merit twice. He is like a screw that never loosens, always escorting the property safety of the people.

Dedicate yourself to the police camp.

Zhang Xinghua was born in an ordinary peasant family. Joining the army was his childhood dream and his greatest wish since then. Since the day he became a soldier, he has the expectation of his hometown elders and is determined to make a career in the army.

Since joining the army, he has to get up half an hour earlier than others every morning, cleaning and doing chores. He has done everything in an orderly way and left his shadow in every corner of the army camp.

During his tenure as an assistant to the squadron leader, he insisted on training, working and studying with the soldiers, and often used his rest time to have heart-to-heart talks with other comrades, to understand the soldiers’ family life, personal hobbies, plans to come to the army, etc., and to accurately understand the ideological pulse of the whole team at any time.

Give up one’s life and forget one’s death.

At 2 pm on October 16th, 2012, a thrilling scene happened on the fifth floor of Building 7, Qingyiyuan Community, Xiadu Street, Chengdong District, Xining City. A man was sitting in the fifth floor window with his one-year-old daughter in his arms because of a family dispute, threatening to jump off the building and commit suicide. He was so excited that he could jump at any time.

At the critical moment, Zhang Xinghua jumped down from the sixth floor, pushed the man into the house with a precise foot, and then quickly entered the house from the window to control him. After this video was exposed on the Internet, it was quickly reprinted by many websites, and the reputation of Xining Fire Fighting "Flying Brother" spread like wildfire.

Train hard, devote yourself to fire fighting and strive for honor

In view of the actual situation of the squadron, Zhang Xinghua made careful preparations and scientific training, rationally arranged the training time and progress, carried out training in various forms, increased ideological education and publicity of tournament competition, popularized advanced training experience and practices, and solved the training problems. He knew how heavy the burden was on his shoulders. When the leader asked him if he could carry two burdens on one shoulder, his answer was only hit the floor’s words: "Ensure to complete the task!"

In participating in the 100-meter attack skill project, Zhang Xinghua quickly completed every small movement with the accumulated experience of long-term training, refined and beautifully transported the last bottle, and with super physical strength and tenacious perseverance, he successfully completed the competition project with a good score of 1 minute and 19 seconds. It has achieved the first good result in this subject in the province, adding a heavy sum to the group points of the squadron.

Under his leadership, the squadron stood out among the 34 participating teams, and the double trunk water supply exercise won the first place in the province and finally won the third place in the group, making a historic breakthrough.

Rescue, no regrets, youth casting police soul.

During the "April 14th" Yushu earthquake in 2010, Zhang Xinghua rushed to Yushu Tibetan Autonomous Prefecture in Qinghai Province to participate in earthquake relief under the unified mobilization of the Provincial Fire Corps. During the 72 hours of gold rescue, Zhang Xinghua worked closely with his squadron comrades to fight day and night, excavating 11 victims and saving about 400,000 yuan of people’s property.

During the flood control and flood fighting in Golmud in July, 2010, Zhang Xinghua was brave and tenacious, charging ahead, risking his life again and again with his comrades, charging at the forefront of flood fighting and rescue, braving wind and rain, coping with floods, building dams, fighting disasters and rescuing on water, and building a series of safety dams. He transported sand and gravel with his comrades-in-arms. When there were not enough people to fill the sand and gravel, he simply bandaged his finger when compiling the barbed wire and continued to work. In this harsh climate and difficult conditions, he fought for seven days in a row and blocked the breach dam with his comrades-in-arms for more than 700 meters.

In the past 10 years, Zhang Xinghua has successively completed more than 680 rescues such as Yushu earthquake relief, Golmud flood control, Zhouqu mudslide in Gansu, and 4.9 textile building fire, rescued and evacuated more than 360 people trapped, and saved more than 35 million yuan in economic losses for the country and people. He explained a soldier’s devotion to fire fighting with practical actions. (Source: Ministry of Public Security)

CCTV News:Driven by the Beijing Winter Olympics, the ice and snow movement has been widely carried out, and the ice and snow that used to be a "cold resource" has gradually transformed into a "hot economy" that drives high-quality development.

Xinjiang, which is rich in ice and snow resources, is now in the hot summer. In the Jiangjunshan International Ski Resort in Altay City, the construction of the tourist service center project is in full swing, and the sound of the scene is rumbling, and the workers are scrambling for the construction period and working together to strive for 2022— Put into use in the snow season of 2023.

Altay’s continued investment in ice and snow facilities lies in the 97% increase in the number of tourists received in the snow season last year. Thanks to this, this year Xinjiang will also complete the construction of Huocheng Ice and Snow Town, the expansion of Nalati Ski Resort and Sailimu Lake Ski Resort. On a nationwide scale, despite the impact of the epidemic, the number of ski tourists in the country has maintained an increasing trend. The ice and snow industry is becoming the new engine of economic development in many areas rich in ice and snow resources.

　　　　　　 Peng Weiyong, Deputy Director of Sports Economics Department of State Sports General Administration:2021— In the snow season of 2022, the number of ice and snow tourists reached 312 million, and the tourism income reached 390 billion yuan. The facilities of ice and snow venues have been greatly improved. Now our skiing population has reached 15 million, and the number of skiers has reached 21 million. On the whole, our scale, social subjects and skiing population are constantly expanding, showing a good trend.

As a country with a late development of ice and snow sports, China has always been considered that ice and snow resources are not rich. However, the research findings of the Institute of Geography of Chinese Academy of Sciences in recent years show that China is rich in ice and snow resources, and there are still a large number of high-quality ice and snow resources that have not yet been developed.

Entrusted by the relevant state departments, the Institute of Geography of Chinese Academy of Sciences began to investigate China’s land ice and snow resources in 2010. It is found that the comprehensive conditions of China’s ice and snow resources are comparable to those of internationally famous ice and snow tourist destinations, such as the European Alps, the Loki Mountains in North America, Northeast Asia, Japan and South Korea, and it is one of the best ski tourism resource-rich areas in the world. In addition to the traditional northeast and north China, especially the northwest region has obvious advantages in key indicators such as vertical drop, snowfall and snow storage period.

Li Yu, researcher of Institute of Geography, Chinese Academy of Sciences:In recent years, we have made a general survey of resources, and initially found that in Xinjiang, the focus is on Altay in Xinjiang, including Ili Prefecture. We believe that it should be in the first echelon in terms of quality, quantity and volume.

According to reports, in 2021, there will be 52 international large-scale ski resorts with more than 1 million skiers in the single snow season, of which 79% will be in the Alps; In this respect, China is still blank and has great potential for future development. However, experts also said that the construction of large-scale ski resorts should be scientifically evaluated from local natural resources, location advantages, environmental protection and other aspects, and it is forbidden to blindly follow the trend of development.

Li Yu, researcher of Institute of Geography, Chinese Academy of Sciences:From the orientation of the main function of the country and the spatial planning of the country, the core area of the clear ecological red line area should be firmly fixed. In addition, in the area south of the Yangtze River, I personally think that outdoor ski resorts should be at least strictly restricted (built) and the development of indoor ski resorts should be encouraged.

　　On August 24th, the Japanese government unilaterally forced the Fukushima nuclear polluted water to be discharged into the sea. This extremely irresponsible move triggered strong opposition from the international community.

　　Japan launches Fukushima nuclear polluted water discharge into the sea.

　　But amid the opposition, there is a "debris flow" that is out of place.The authorities in Democratic Progressive Party, Taiwan Province not only don’t object to the Japanese government’s discharge of nuclear polluted water, but also take the initiative to "whitewash" the aquatic products imported from Japan, claiming that "there is no risk, so it will not be banned for the time being".Be ridiculed as a stage "‘ Help ’ On the 26th, Xie Changting, the representative of Japan, even made a strange remark on social media, saying that "trace radioactive elements are beneficial to the body", which is really "‘ Help ’ Day "has no bottom line.

　　Previously, the Democratic Progressive Party authorities had "whitewashed" Japanese Fukushima food with doubts about radioactive material residues, called "nuclear food" a "blessing food", and opened the import of "nuclear food" regardless of public opposition. This time, as always, I am groveling in front of Japan.

　　In fact, from the American "Lai pig", the Canadian "mad cow" to the Japanese "nuclear food", the Democratic Progressive Party authorities have become habitual offenders in importing problem foods.

　　Today, Master Tan will talk to you about the Democratic Progressive Party authorities’ trading people’s food safety.

It’s impossible to prevent!

The people’s dining table on the island has fallen.

　　"To carefully identify the origin mark, buy pork depends on whether it is the United States ‘ Lai pig ’ Buying beef depends on whether it is ‘ Add cattle ’ Buying aquatic products depends on whether it is Japanese or not, beware of disaster! "

　　This is the spit of an island friend of Tan Zhu. He said that when buying food in Taiwan Province, we should pay special attention to the place of origin."The Democratic Progressive Party authorities have poisoned the dining tables of Taiwan Province people badly in recent years!"

　　A store in TaipeiHanging "Taiwan Province Pig"Sign to attract customers

　　Master Tan’s search found that this island friend’s worry was by no means a mountain out of a molehill.

　　In addition to Japan’s "nuclear food", which has once again become the focus of discussion on food safety on the island because of Japan’s nuclear sewage discharge, just two months ago, Taiwan’s administrative agencies also decided to open the import of Canadian full-age beef with concerns about mad cow disease. Canada has been repeatedly upgraded by the World Organization for Animal Health (WOAH) for mad cow disease.

　　Experts studying food safety on the island told Tan Zhu that the incubation period of BSE is as long as several years and the mortality rate of infected people is extremely high. Therefore, Taiwan Province’s "Food Hygiene Management Law" clearly stipulates that beef imports should be banned in the territories where BSE occurs within 10 years.Canada, which was just exposed to mad cow cases at the end of 2021, has obviously not passed the "risk period".

　　There are also media reports on the island that before confirming the import of "plus cattle", Taiwan Province Food and Drug Administration went to Canada for on-the-spot inspection, but did not check the slaughterhouses mainly for cattle over 30 months old (generally, cattle with mad cow disease are about 39 months old).Simply ignore the key points and go through the motions, and regard food safety as a child’s play.

　　This year, the Democratic Progressive Party authorities also opened up the import of Japanese cooked pork. However, some media on the island disclosed that there have been several cases of swine fever in Japan in recent years, which spread to more than 10 counties. In 2020, it lost the qualification of "swine fever clearing country" recognized by the World Organization for Animal Health (WOAH).Japanese pork can’t be sold to European and American markets at all, and only Taiwan Province is the "take-over man".

　　Also imported by Democratic Progressive Party authorities are American pork containing ractopamine, Japanese "nuclear food" mentioned above, and even Japanese imported strawberries found to contain banned pesticides.Democratic Progressive Party authorities can relax the standards of pesticide detection specifically for them, opening the door for Japanese "poisonous" strawberries.

　　No wonder Tan Zhu’s friends on the island are so uneasy about imported food.

　　Japanese imported strawberries containing banned pesticides were detected on the island.

Eat by the head!

Democratic Progressive Party authorities harbor evil intentions.

　　In order to safeguard the safety of the dining table, in recent years, people on the island frequently took to the streets to express their demands.

　　At the end of 2020, dozens of groups in Taiwan Province held the largest "Autumn Fight" parade in history, shouting "Anti ‘ Lai pig ’ "Take care of food safety", many parents took part in the demonstration with their children and asked the Democratic Progressive Party authorities: Have you ever cared about the health of the next generation?

　　People on the island marched against the import of American "Lai pig"

　　There are also non-governmental organizations that published a love letter saying, "The Democratic Progressive Party authorities are willing to be obedient and open to the American people ‘ Lai pig ’ Imports seriously endanger people’s health. ""People don’t want to be victims of politics, and the most humble hope is health. "

　　Similarly, as early as "anti ‘ Nuclear food ’ In the referendum, the people on the island rejected Japan’s "nuclear food" imports with 7.79 million votes. After Japan forcibly discharged nuclear polluted water into the sea, the anti-Japanese "nuclear food" public opinion on the island once again reached the boiling point. Some netizens on the island left a message asking the Democratic Progressive Party authorities, "How much do you sell for the health of Taiwan Province people?" "Is the life of Taiwan Province people worthless?"

　　People on the island oppose Japan’s "nuclear food"

　　Regrettably, the Democratic Progressive Party authorities have always been perfunctory about the questions and protests of the people on the island, and have drawn all kinds of "big cakes" that have not yet been realized and cannot be realized.

　　Tan Zhu noticed that when the import of Lai Pig was opened, Tsai Ing-Wen declared that the decision could effectively promote "Taiwan-US relations" and help promote the "bilateral trade agreement" between Taiwan and the United States.

　　On the issue of "adding cattle", Mason Lee, deputy director of Taiwan’s foreign affairs department, also publicly stated that Canada will be the chairman of the Executive Committee of the Comprehensive and Progressive Trans-Pacific Partnership Agreement (CPTPP) next year, and opening up the import of Canadian full-age beef will have a positive effect on Taiwan Province’s accession to CPTPP.

　　After opening the "nuclear food" to the island, Tsai Ing-wen and Su Zhenchang frequently talked, suggesting that Taiwan Province’s move to open the Japanese "nuclear food" was "right", which would help strengthen the "Taiwan-Japan relationship" and facilitate Taiwan Province’s entry into CPTPP.

　　Produced by netizens on the island

　　Experts studying food safety on the island told Tan Zhu,The Democratic Progressive Party authorities’ wide-open door and "taking over" the problem food everywhere regard selling the health and well-being of Taiwan Province people as a "stepping stone" to expand the "international space". In the final analysis, it is for their political self-interest. These shameless politicians have sharpened their heads and want to join CPTPP, hoping to reach a so-called "value alliance" and "interest alliance" with "foreign masters" such as the United States and Japan, and create the illusion of "support from the international community" in order to defraud votes on the island.

　　However, Mr. Tan must remind the Democratic Progressive Party authorities that Taiwan Province, as a part of China, must take the one-China principle as the premise to join any international organizations and participate in any international activities.The Democratic Progressive Party authorities’ flattery of foreign countries to sell Taiwan has only resulted in "lip service", and what is more, the "foreign masters" have made more and more unscrupulous demands on Taiwan Province.

　　The "poisonous food" of the people on the island is doomed to be "free food". The Democratic Progressive Party authorities have ignored the health and well-being of the people on the island, and they have no bottom line to flatter foreign countries and harm Taiwan. They are also doomed to blame and be spurned.

　　Medical technicians in Cihu High-tech Zone, Ma ‘anshan City, Anhui Province are developing COVID-19 pharmaceutical core intermediates. Wang Wensheng photo/bright picture

　　Workers of a pharmaceutical company in Shijiazhuang, Hebei Province work in the pharmaceutical production workshop. Xinhua news agency

　　　 [Endeavour, New Journey, New Era, Great Change]

　　　 Since the reform of evaluation in 2015, National Medical Products Administration has approved 95 innovative drugs and approved 155 innovative medical devices to be listed.

　　　 Five Covid-19 vaccines were approved for conditional marketing, two Covid-19 vaccines were approved for emergency use, and 34 vaccine varieties with five technical routes entered clinical trials.

　　　 106 novel coronavirus detection reagents were approved, including 38 nucleic acid detection reagents, 37 antibody detection reagents and 31 antigen detection reagents.

　　　 "The quality of registration application materials is not high, and it needs to be supplemented and improved many times during the review process, which seriously affects the efficiency of review and approval; Repeated construction and application of generic drugs, vicious competition in the market, and the quality of some generic drugs is far from the international advanced level; The listing approval time of new drugs urgently needed in clinic is too long, and drug research and development institutions and researchers cannot apply for drug registration, which affects the enthusiasm of drug innovation. "

　　　 This is a frank and incisive analysis of drugs and medical devices related to people’s lives and health in a the State Council document seven years ago. This analysis resonates with the confusion of the people: Why are some drugs "slower" to market in China than in foreign countries? Why do some people go overseas to purchase medicines?

　　　 The full name of the the State Council document is Opinions on Reforming the Examination and Approval System of Medicines and Medical Devices, which was issued in August 2015, thus kicking off the reform of the examination and approval system of medicines and medical devices in China (hereinafter referred to as the examination and approval reform). Especially since its establishment in 2018, National Medical Products Administration has continuously deepened the reform of evaluation, encouraged the innovation of drugs and medical devices, improved the quality of drugs and medical devices, increased effective supply, and effectively guaranteed people’s health and life safety.

1. The backlog of registration applications has been solved.

　　　 The quality of drugs and medical devices is related to everyone’s health and safety, which is the original intention of implementing the review and approval system. However, if the evaluation efficiency is too low, it will lead to the lag of product listing time, which will also affect people’s health and safety. After all, disease waits for no one.

　　　 Take drugs as an example. In the past, the backlog of drug registration applications in China was serious, with a maximum of 22,000 applications. Many drugs have to wait several years for approval after they apply for registration. Pharmaceutical companies are helpless and patients are miserable.

　　　 How to speed up the review? This is the first problem to be solved in the reform. The drug regulatory authorities, seeing the move, launched a series of powerful measures — —

　　　 Full implementation of the implied license system for 60-day expiration of drug clinical trials, which is one-third shorter than the 90-day review time limit before the reform.

　　　 We will establish and improve the procedures for accelerating the listing and registration of drugs, optimize the review and approval process, and give priority to the clinical shortage of drugs, anticancer drugs, drugs for children, drugs for rare diseases, drugs for major infectious diseases, vaccines urgently needed for disease prevention and control, and innovative high-end medical devices, thus greatly shortening the review time limit.

　　　 Drugs that show efficacy in early clinical trials can be conditionally approved for marketing and used in urgent need patients who can’t wait any longer.

　　　 … … … …

　　　 As a drug technical evaluation institution, National Medical Products Administration Drug Evaluation Center has also strengthened the management of evaluation items, refined the evaluation sequence, strengthened the management of time limit, set up special groups, increased reviewers, revised the evaluation points, standardized technical requirements, etc., and the evaluation standards, quality and efficiency of drugs have been greatly improved.

　　　 "From the peak in 2015, there was a backlog of more than 20,000 applications. By 2018, more than 90% of them were reviewed within the time limit, and China’s drug review and approval entered the fast lane." The relevant person in charge of the Department of Drug Registration of National Medical Products Administration told the reporter that, for example, in terms of new drugs urgently needed overseas, by the end of 2021, 51 new drugs urgently needed overseas were approved for listing, among which the review of rare diseases drugs was completed within 3 months, and the review of other drugs urgently needed clinically was completed within 6 months, which greatly shortened the time for listing new drugs urgently needed overseas in China.

2. The innovation enthusiasm of the pharmaceutical industry has been stimulated.

　　　 The backlog of applications has been solved, and the speed of drug listing has been accelerated. However, in order to meet the people’s drug demand, new drugs need to be put on the market continuously. Encouraging drug innovation is the core of evaluation reform.

　　　 In 2015, the Opinions on Reforming the Examination and Approval System of Drugs and Medical Devices raised the standards for drug approval, and changed the new drugs from "drugs that were not marketed in China" to "drugs that were not marketed in China or abroad", that is, "global new". Two years later, the General Offices of the General Office of the Central Committee of the CPC and the State Council issued the Opinions on Deepening the Reform of Review and Approval System and Encouraging the Innovation of Pharmaceutical and Medical Devices, and made special arrangements for the innovation of pharmaceutical and medical devices.

　　　 The reporter learned that in order to encourage the research and development of innovative drugs and medical devices, National Medical Products Administration not only gave support in priority evaluation, but also formulated a series of technical guiding principles, such as "Technical Requirements for Application for Pharmaceutical Common Problems in Phase I Clinical Trials of Innovative Chemicals", to guide the application for research and development of innovative products. Reviewers will also take the initiative to communicate with R&D producers in key review links such as pre-clinical, clinical and pre-listing, so as to avoid detours.

　　　 "The review reform encourages clinical value-oriented drug innovation, optimizes the review and approval procedures for innovative drugs, and accelerates the review of innovative drugs that are urgently needed in clinic, which greatly stimulates the research and development vitality of pharmaceutical companies." The relevant person in charge of Renfu Pharmaceutical Group Co., Ltd. told reporters that in recent years, a number of new drugs have been approved for listing in this enterprise, and new breakthroughs have been achieved in innovation capability.

　　　 Among many reform measures, the system of drug marketing license holders deserves attention. Previously, only pharmaceutical manufacturers could apply for drug registration. In order to register drugs, researchers and research institutions must first invest and build factories themselves. This management system of product registration and production license is not conducive to drug innovation. In 2015, China launched a pilot system of drug marketing license holders in 10 provinces and cities, and drug research and development institutions and researchers can apply for registered drugs. Expert analysis pointed out that this move reduced the capital investment and time cost of drug developers, and new drugs could be listed three to five years in advance. In 2019, the drug marketing license holder system was written into the newly revised drug administration law and was fully implemented nationwide.

　　　 According to National Medical Products Administration, in recent years, China has made great progress in the development of innovative drugs. From 2018 to 2021, the number of innovative drugs approved for marketing increased year by year, with 11, 12, 20 and 45, respectively, including Covid-19 vaccines and clinically urgent therapeutic drugs in the fields of tumors, immune system diseases and rare diseases. The pace of medical device innovation is also accelerating. In 2021, 35 innovative medical devices were approved for listing, which is the largest number of innovative products approved in recent years.

3. Consistency evaluation improves the efficacy of generic drugs.

　　　 In recent years, many drugs that were originally expensive began to reduce their prices. Careful observation shows that there is a "hero" behind the decline in drug prices — — Generic drugs.

　　　 Innovative drugs provide new options for treating diseases and saving lives, but for the vast majority of patients, generic drugs are their life. According to National Medical Products Administration, China’s modern pharmaceutical industry started late, and the production of drugs is mainly imitation. More than 95% of the chemicals that have been approved for marketing are generic drugs.

　　　 Generic drugs are imitations of the original drug after the patent protection period expires, and the price is much lower than that of the original drug. In the past, China’s generic drug evaluation and approval standards were not high, and there was a lack of high-quality generic drugs, and the curative effect was very different from that of the original drug.

　　　 Improving the quality and efficacy of generic drugs is an important goal of evaluation reform, and the solution is the consistency evaluation of generic drug quality and efficacy — — For generic drugs that have been approved for marketing, the evaluation should be carried out according to the principle of consistency with the quality and efficacy of the original drug. The core is that generic drugs should reach the level consistent with the original drug in quality and efficacy, and can replace the original drug in clinic.

　　　 "There are several key issues in carrying out consistency evaluation, one is the selection and determination of reference preparations, the other is the determination of technical standards, and the third is to strictly follow the procedures." According to the person in charge of National Medical Products Administration, the Bureau ensured the smooth development of generic drug conformity evaluation by improving the evaluation system, strictly evaluating standards, strengthening service guidance and optimizing the workflow. At present, 4677 specifications of generic reference preparations have been published, and 2044 specifications and 437 varieties have been applied for through consistency evaluation.

　　　 Consistency evaluation puts generic drugs on the right track, and ultimately benefits the people. Since the pilot of centralized drug procurement and use organized by the state was launched nationwide in 2019, a number of domestic generic drugs won the bid. Medical insurance, health insurance and other departments have organized medical institutions to carry out research on 14 representative generic drugs that won the bid, and confirmed that these 14 generic drugs that passed the consistency evaluation are clinically equivalent to the original drugs. Generic drugs with the same efficacy as the original drug are not only cheaper, but also further reduce the price of the original drug under competitive pressure, greatly reducing the burden of patients.

4, emergency review and approval for epidemic prevention and control to provide a strong guarantee.

　　　 4 days, which is the time for China to complete the review and approval of the first Covid-19 nucleic acid detection reagent and sequencing reagent in the world.

　　　 On January 20, 2020, National Medical Products Administration Instrument Center started the emergency work overnight, and the reviewers stayed up all night to connect with the enterprises one by one, and the review and research and development were carried out simultaneously. On January 26th, the first batch of four in vitro diagnostic reagent products were approved for marketing, which provided an effective detection method for the first line of anti-epidemic.

　　　 The outbreak of epidemic situation in COVID-19 challenges the evaluation reform. Xu Jinghe, deputy director of National Medical Products Administration, said at the Boao Forum for Asia in 2021 that the role of drug supervision departments in epidemic prevention and control has changed, from reviewers to instructors, working with enterprises to speed up product listing.

　　　 It is understood that National Medical Products Administration made every effort to carry out emergency review and approval during the epidemic. Five Covid-19 vaccines have been approved for conditional marketing, two Covid-19 vaccines have been approved for emergency use, and 34 vaccine varieties from five technical routes have entered clinical trials. Organized the formulation of three technical guidelines for research and development of therapeutic drugs in Covid-19, approved 58 applications for clinical trials of therapeutic drugs in Covid-19, and approved the registration and listing of Qingfei Detoxification Granules, Huashi Detoxification Granules and Xuanfei Detoxification Granules. 106 novel coronavirus detection reagents were approved to effectively meet the needs of epidemic prevention and control.

　　　 The epidemic is not over yet, and the emergency review and approval is still going on. As long as people’s health needs it, the evaluation reform will not stop. The drug supervision departments and reviewers have been speeding up on the road of realizing healthy China, so as to run out of acceleration for people’s health.

　　　 (Reporter Chen Haibo)

Zhongxin. com, Chengdu, September 6 (Reporter He Yuqing) The reporter learned from the Sichuan Provincial Committee of the Communist Youth League on the 6 th that the Sichuan Youth Development Foundation, the Sichuan Youth Federation and the Sichuan Young Entrepreneurs Association jointly issued the "Proposal for Emergency Relief Action of the" 9.5 "Luding Earthquake Hope Project in Sichuan Province" on the same day, urging caring enterprises and individuals from all walks of life to donate generously and actively support the earthquake-stricken areas. The proposal also announced the donation method and contact information of material donation.

　　The original text of the proposal is as follows:

　　Proposal for Emergency Relief Action of Hope Project of "9.5" Luding Earthquake in Sichuan Province

　　At 12: 52 on September 5, 2022, an earthquake of magnitude 6.8 occurred in Luding County, Sichuan Province, with a focal depth of 16 kilometers. The disasters in Luding County of Ganzi Prefecture and Shimian County of Ya ‘an City in our province were serious. Sichuan people once again face the pain of the earthquake. At this moment, the disaster area needs our help!

　　In order to help teenagers and families with special difficulties in disaster areas get out of the shadow of the earthquake as soon as possible, return to school, resume production and rebuild their hopes, Sichuan Youth Development Foundation, Sichuan Youth Federation and Sichuan Young Entrepreneurs Association jointly launched "Sichuan Province ‘ 9·5’ Luding Earthquake Hope Project Emergency Relief Action ",mobilizing caring enterprises and individuals from all walks of life to support the earthquake-stricken areas. According to the current situation, the three contents of this emergency relief operation are drawn up: first, to raise much-needed living security materials for the disaster-stricken areas; The second is to raise funds to carry out humanistic and mental health care for the people in the disaster areas; The third is to raise grants and relief funds for young students in disaster areas (donate 1000 yuan to fund a primary school or junior high school student in disaster areas; Donate 3000 yuan to support a high school or vocational school student in the disaster area; Donate 5000 yuan to help a college freshman in the disaster area; Donate 10000 yuan to help a student and family with special difficulties in the disaster area.

From August 15th to 17th, Leshan City, Sichuan Province ushered in a new round of heavy rainfall. Coupled with the water from the upper reaches of the Three Rivers, rivers in Leshan City generally flooded. The water levels of Qingyi River and Minjiang River rose sharply, and suffered two rounds of flood peak crossing. The flood peak water level at Xiaogongzui where the three rivers meet was 363.15m, and the flow rate was 23,900m3/s, which was the biggest flood since 1995, causing the dike in Xiaogongzui section of Leshan to overflow by 0.2m to 0.6m..

Compared with the previous round of rainstorm and flood, this round of rainstorm has a wide coverage, large rainfall level and strong hourly rainfall. The flood involves a large number of rivers and the increase is large, making flood control and disaster relief more arduous. In the face of severe tests, Leshan City moved up and down at the news of the flood season, made careful arrangements, made full efforts to meet the challenges, and implemented various flood control and disaster reduction measures in detail to ensure the safety of people’s lives and property.

Rapid mobilization and deployment

"Adhere to the people first, life first, always maintain a wartime state, always be ready, resolutely win the hard battle of flood control and disaster relief, and ensure that the people of the city spend the flood season safely and smoothly." "We must not be afraid of fatigue, continue to fight, and go all out to ensure the safety of people’s lives and property and ensure the safety of the flood season." Leshan Municipal Party Committee and Municipal Government attached great importance to flood control and disaster reduction. Facing this round of heavy rainfall, the main leaders of Leshan Municipal Party Committee and Municipal Government presided over the video dispatching meeting of flood control and disaster reduction in the whole city, deployed the response work, and went to the front line to supervise the flood control and disaster reduction work.

"All levels and departments should make use of the only 30-hour golden gap between the two rounds of heavy rainfall, pay close attention to verification and investigation, pay close attention to danger removal and reinforcement, pay close attention to the Tengku to meet the flood, and pay close attention to the replenishment of flood control materials." According to the trend and forecast of water and rain conditions, Leshan Flood Control and Drought Relief Headquarters timely issued the Emergency Notice on Doing a Good Job in Post-disaster Recovery and Active Response to Storm and Flood in the Later Period, the Emergency Notice on Doing a Good Job in Flood Prevention for Ships on Water, the Emergency Notice on Doing a Good Job in the Prevention of Heavy Rainfall in this Round and the Emergency Notice on Doing a Good Job in Flood Prevention in Leshan Section of Qingyi River, and the current flood of Qingyi River was controlled at 15,000 cubic meters per second (once in 20 years).

Leshan City Flood Control and Drought Relief Headquarters held a video dispatch meeting in time to dynamically judge the trend of rain and water conditions 24 hours a day. On August 15th, it started the city’s level IV flood control emergency response, and on August 16th, it was upgraded to the city’s level III flood control emergency response. Targeted arrangements were made for the deployment of response preparations, and all flood control responsible persons at all levels and those responsible for monitoring, inspection, early warning, transfer, rescue and resettlement at the "last mile" grassroots level arrived at their posts in time.

Prepare in advance

In the face of this round of heavy rainfall, all parts of Leshan maintained a wartime state, mobilized and deployed early, and implemented various flood control and disaster reduction measures in detail to ensure safe flood control.

All parts of Leshan made overall plans to do a good job in the last round of after-rain verification and the new round of before-rain investigation of heavy rainfall, and carried out full coverage investigation on the coastal areas of major rivers, hidden points of ground disasters, reservoirs and dams, construction sites, etc., and timely organized rescue teams to carry out danger removal and danger removal for existing safety hazards. If the rectification cannot be completed in a short period of time, all the people will be responsible for monitoring and duty, and an emergency plan will be formulated. Comb and anchor all ships, and resolutely put an end to ships out of control.

All parts of Leshan once again increased the propaganda of people’s risk-avoidance transfer in key areas such as hidden danger points of ground disasters and dams in the river center, once again organized the masses to be familiar with the transfer route, and actively educated and guided the masses to enhance their awareness of active risk-avoidance. Strictly implement the requirements of "Three Avoidances" and "Three Emergency Evacuations", make every effort to organize people to avoid danger and transfer, and resolutely "turn around and turn around". As of 23: 00 on August 17th, Leshan has transferred 18,341 people. Among them, 5093 people were transferred from the dam in the middle of the river, 3545 people were transferred from the ground disaster, and 9703 people were transferred from the mountain torrents and low-lying areas of rivers. Actively coordinate the municipal traffic police departments to carry out temporary parking in heavy rainfall, and effectively meet the needs of residents’ vehicles to avoid risks.

The flood control safety of industrial and mining enterprises has been strengthened in Leshan, and 29 hazardous chemicals enterprises in the city have implemented flood control measures and temporarily stopped production. There are 35 coal mines in the city, and 13 are in normal production. All of them were temporarily suspended before this round of heavy rainfall. There are 125 non-coal mines and tailings ponds, all of which were temporarily suspended before this round of heavy rainfall.

Hidden dangers of A-level scenic spots and farmhouses were inspected in all parts of Leshan. As of 14: 00 on the 17th, ticket sales in six scenic spots in the city were suspended. Giant buddha suspended the sale of mountain tickets from August 17th, while the daytime tour of the Yangtze River, the "night tour of Sanjiang" and the "night tour of Lingyun Mountain" continued to be suspended. Emei Mountain Scenic Area temporarily stopped selling tickets and sightseeing tickets at 14: 00 on the 16th, and the scenic area will adjust relevant measures according to the rainfall.

All-out emergency rescue

Affected by the heavy rainfall in the upper reaches, the water level of Minjiang River keeps rising, and the water level exceeds the warning level many times from August 16th to 17th. At 22: 00 on August 16th, the flood peak flow of Wuyou Temple water level station in Minjiang River was 23,900 cubic meters per second, which caused the foundation and slope protection of Laojiangba River embankment in Jindeng Village of Leshan High-tech Zone to be destroyed by 400 meters, seriously endangering the safety of the river embankment, and threatening the safety of 523 households and 1,756 people behind the embankment. The flood control headquarters of Leshan High-tech Zone started the Class III emergency response to flood control in time, and the villages and towns organized villagers to transfer to avoid danger in time, and all 1748 people were transferred except the rescue personnel. More than 500 rescue workers, including armed police, firefighters and militia, immediately entered the actual combat state and started construction 24 hours a day. By 23: 00 on August 17th, a total of 15 rescue machines were put into use, more than 300 tetrahedrons were thrown, more than 1,000 tons of bags were transported and 25,000 woven bags were used for slope protection, and the collapsed dike was robbed and protected, which quickly controlled the danger. Many communities and underground garages in downtown Leshan are flooded, and relevant departments have piled up more than 5,000 sandbags for flood control in many dikes, strengthened defensive duty, set up warning lines and warning signs, and implemented special personnel control to prevent the river from gathering. Dispatch emergency patrol and rescue teams, dispatch large-scale pumping and drainage facilities, power generation facilities and emergency patrol vehicles. For the 27 property communities affected by the disaster, we will fully organize rescue and disaster relief. At the same time, organize personnel to conduct 24-hour on-site duty and inspection on important infrastructure such as bridges, water supply and dikes along the river.

In order to ensure the safety of transportation, Leshan City has strengthened the safety supervision of "two passengers and one danger" enterprises, buses connecting every village and ferries crossing the ferry, and strengthened the investigation of accident-prone sections, dangerous sections, sections facing the water and cliffs, and sections facing the ridge. During this round of rainstorm and flood, the city’s roads collapsed by 3,000 cubic meters, and the broken road at K1802+650 on the G348 line of Qiqigou, San ‘e Village, Shawan District, National Highway 348 is being repaired. Seven broken roads in rural areas have been rushed through, 27 lines have been suspended, 2 vehicles have been stopped, 142 rural passenger vehicles have been stopped, and 314 ships of various types have been fixed.

As of 23: 00 on August 17th, nine counties (cities, districts) in Leshan City were affected to varying degrees in this round of heavy rainfall weather, with 30,242 people affected, and no one was reported missing due to the disaster, and the affected area of crops was 1,268.53 hectares. The city has dispatched more than 9,000 rescue forces and 1,385 rescue vehicles, rescued 28 trapped people, eliminated 115 geological hazards, eliminated 9 urban waterlogging, restored 484 roads and restored 99 power lines.

According to the forecast of the meteorological department, there will still be heavy rainfall in Leshan City from the evening of August 17th to August 18th, with the rainfall of 60-90 mm in the whole city, in which the local area in Shizhong District, Shawan District, wutongqiao district, Jiajiang County, Emei Mountain City, Qianwei County and Muchuan County can reach more than 100 mm, with the maximum rainfall of 130-160 mm and the maximum hourly rainfall of 40-60. At the same time, Ya ‘an, Meishan and Chengdu in the upper reaches issued blue rainstorm warnings. Leshan city, the city’s emergency response thinking is not relaxed, so that measures are not reduced, the intensity is not reduced, to ensure the safety of the people in the city.

(This article was first published in "Movie Rising Potential", welcome WeChat to search filmmore for attention)

　 1905 movie network exclusive feature Just two months after the topic of the year attracted people’s attention to art films in the summer file, another art film bravely landed in early September in the crisp autumn.

　 The last film film, 4K restoration, tens of millions of investments, ten years of creative process, Berlin Silver Bear Award … … The blessings of various auras have made this work full of expectations before it was shown … … However, after the screening, many viewers said that "seeing a face of embarrassment" made this film full of topicality.

　 However, the film’s creative team was obviously full of confidence in the film. As soon as it was released, it was announced that the film would apply for the "Oscar for Best Foreign Language Film". In the case of the excellent overseas copyright situation of the film, the box office performance of 2.689 million in five days in the mainland does not seem to bring much pressure to the film … …

　 Although pretending to be a senior literary dog for many years, unfortunately, after attending the screening of the film on September 7, Zi Shijun also became a member of the "force army". In order to solve all kinds of doubts about this film, Zishijun specially found Wang Mi, the producer of the Yangtze River Map, and listened to how he interpreted this annual masterpiece:

Don’t do commercial films because there is too much garbage, and it is not difficult for director Yang Chao to communicate.

Zi Shijun:You once said that the most profitable thing in China is literary films. As a producer, how do you choose between business and art?

　

Wang Wei:My concept of "making money" here is not to say how much money can be earned like a big commercial film, because the most important thing for art films is to recycle.

　 Art films have a longer vitality, so it has more possibilities of overseas distribution, and it can actually be profitable through various distribution on the Internet and media distribution. In fact, you can calculate the account of the roadside picnic. Although it didn’t earn much money, it was profitable. These premises are necessary, and it is not just that sentence that can judge this matter.

　

　 There is no special difference between commercial films and literary films. The reason why I don’t want to do mainland commercial films in recent years is because there is too much rubbish in the market, all of which are fake commercial films. I will watch many domestic films, and I will be disappointed after watching them. The quality of production is relatively rough, and most of the themes and types are too simple. After you watch it, you will mix several films together.

stage photo

　 What I prefer to do is actually genre movies, movies with certain characteristics, including the Yangtze River Map, which has distinctive characteristics, including Wu Ershan’s Knife Seeing Smile, which I did before. In fact, it is also a work with distinctive themes and personalities. I think what China’s films lack are different types, and a variety of markets are benign.

　

Zi Shijun:As a producer, both your two works and The Map of the Yangtze River are related to the Yangtze River and the Three Gorges. Is there some kind of complex in them?

　

Wang Wei:In part, I did shoot a lot of movies around the Yangtze River.

　 I’m a Mongolian, but I don’t really remember much about the Yangtze River. But when you are filming for a long time, you will feel that the great river in China has a deep cultural background, because the history of the Yangtze River is far longer than that of China. If you are on the river, you will be moved by many things inexplicably.

The Yangtze River in The Three Gorges Good Man is another flavor.

　 The Yangtze River in The Three Gorges Good Man is completely different from that in The Yangtze River Map. The Yangtze River in the Yangtze River Map has many magical things. Sometimes you think it is not real, and even think it is a made scene. In fact, when you look at her with different eyes, there will be different degrees of relevance, and it is possible to make a science fiction film in the future.

　 I witnessed the rising water level of the Yangtze River, which flooded the historic sites such as Fengjie Old Town. This means that there are still cities lying at the bottom of the Yangtze River. If you think about it, there will be a lot of mystery and science fiction in it. It can be made into that kind of movie.

　

Zi Shijun:Yang Chao is an academic director who is more "axis" and "artist". As a producer, how can you communicate and coordinate with him?

Wang Wei:In fact, Yang Chao is a particularly easy person to communicate with. If everyone agrees on some artistic views, creative direction, or likes and dislikes, it is actually very easy to communicate. Some producers will say that there are obstacles in communicating with the director. I think the obstacle is that everyone has not found the same context in communication, so they need to put themselves in other’s shoes and think about what he is thinking.

Yang Chao, a director with long hair and resembling a "metal warrior", is actually not difficult to communicate with.

　 Yang Chao likes heavy metal and Goth, so do I. I graduated from the Recording Department of the Film Academy. In the creation of many sounds and spaces, I may sometimes have more understanding of sounds than the director. We may communicate more professionally, rather than saying what I want you to do.

　

　 I’m the best recording producer. I graduated from the recording department, and I have 8 years of music professional background (Zishijun: This is quite unexpected, we rarely hear that producers graduated from the recording department). I learned recording technology so badly (laughs) that I became a producer.

Next page: Qin Hao always plays literary films because the market for literary films is too small and there are too few character actors, which is particularly terrible.

Xinhua News Agency, Guangzhou, August 11th (Reporter Xiao Sisi) The Guangdong Provincial Health and Wellness Commission issued a health reminder on the prevention and control of dengue fever. At present, Guangdong has entered the local epidemic season of dengue fever, and the imported cases of overseas infection and local cases are gradually increasing. The Guangdong Provincial Health and Wellness Commission reminded that dengue fever spreads rapidly, and there is no specific treatment drug. Severe cases can cause severe bleeding, shock and even death. Dengue fever can be prevented and controlled, and the key lies in prevention.

According to the relevant person in charge of the Guangdong Provincial Health and Wellness Committee, dengue fever in Guangdong Province is mainly transmitted through the bite of Aedes albopictus (Aedes albopictus), eliminating mosquito breeding sites (indoor and external water accumulation in various homes and workplaces), killing adult mosquitoes and preventing mosquito bites by individuals are key measures for dengue prevention and control.

In addition, travel to prevent mosquitoes and keep up with the awareness of disease prevention. Travellers who are going to areas with dengue fever should take mosquito prevention measures, such as wearing light-colored long-sleeved underwear and using mosquito repellent containing deet. If you have fever, skin flushing, muscle and bone pain and other symptoms within 15 days after traveling in dengue endemic areas, you should seek medical treatment as soon as possible, and explain the travel history and health status of your colleagues to your doctor. Patients who have been diagnosed with dengue fever in medical institutions should actively cooperate with the hospital to do isolation treatment and actively prevent the occurrence of serious diseases.

　　Damper device of Shanghai World Financial Center photographed on September 13th. The device has two sets on the 90th floor (about 394m above the ground), each weighing 150t, to reduce the shaking of the building caused by strong wind. Xinhua news agency

　　Affected by the typhoon "Candu", it has been stormy in Shanghai since September 13th. From the ground to the sky, hard-core technology helps Shanghai prevent typhoons. In Xuhui District Urban Operation Management Center, the depth of ground water, fallen trees on the roadside, and all kinds of drainage emergency situations in the area are monitored in real time on the flood control and typhoon prevention command platform. On the skyscraper in Lujiazui, Pudong, the damper of vibration reduction and pendulum reduction device plays the role of "town building artifact" and guards the city skyline.

　　Damper device of Shanghai World Financial Center photographed on September 13th. The device has two sets on the 90th floor (about 394m above the ground), each weighing 150t, to reduce the shaking of the building caused by strong wind.

　　On September 13th, technicians of Shanghai World Financial Center checked the shaking of damper device during typhoon. The device has two sets on the 90th floor (about 394m above the ground), each weighing 150t, to reduce the shaking of the building caused by strong wind.

　　The eddy current pendulum tuned mass damper is located at the 126th floor of Shanghai Tower. This damper is independently developed by China and weighs 1000 tons. When the building is shaken by the wind force, the inertia of the damper mass produces a reaction force, which produces a reverse swing and plays a role in reducing vibration and swing (photo taken on July 27).

　　The "Shanghai Eye" art sculpture above the "eddy current pendulum tuned mass damper" on the 126th floor of Shanghai Tower (photo taken on July 27th).

　　On September 13th, the staff placed sandbags for flood control at the entrance and exit of sunken plaza in Shanghai Center.

　　Pudong Lujiazui skyscraper photographed on September 13th.

　　On September 13th, the staff used straps to fix the billboards around Shanghai Tower.

　　On September 14th, the command platform for flood control and typhoon prevention was filmed in Xuhui District Urban Operation Management Center, Shanghai.