CCTV News:On April 11th, the National Internet Information Office began to solicit opinions from the public on the Administrative Measures for Generative Artificial Intelligence Services (Draft for Comment). According to experts’ analysis, the Draft for Comment puts forward multi-level supervision opinions, emphasizes the protection of rights and interests, and prevents "abuse" behavior, which contributes to the healthy development of generative artificial intelligence technology in China.

　　There are 21 articles in the Exposure Draft, which defines "generative artificial intelligence" as a technology that generates text, pictures, sounds, videos, codes and other contents based on algorithms, models and rules, and clarifies that "the state supports independent innovation, popularization and application, and international cooperation of basic technologies such as artificial intelligence algorithms and frameworks, and encourages the priority use of safe and reliable software, tools, calculation and data resources".

　　According to the "Exposure Draft", the provision of generative artificial intelligence products or services should comply with the requirements of laws and regulations, respect social morality, public order and good customs, and prohibit illegal acquisition, disclosure and use of personal information, privacy and trade secrets. Before using generative artificial intelligence products to provide services to the public, it is necessary to report to the national network information department for safety assessment, and be responsible for the legality of the pre-training data of generative artificial intelligence products and the source of optimized training data. Pre-training and optimized training data for generative artificial intelligence products shall comply with the requirements of laws and regulations, and shall not contain any content infringing intellectual property rights. If the data contains personal information, it shall obtain the consent of the subject of personal information, and ensure the authenticity, accuracy, objectivity and diversity of the data.

　　On the user side, the user should be required to provide real identity information in accordance with the regulations, and the service should be suspended or terminated if violations of laws and regulations, business ethics and social ethics are found, including engaging in online speculation, malicious posting and comments, creating spam, writing malicious software, and implementing unfair business marketing.

　　With the hot market of ChatGPT, the public’s awareness of generative artificial intelligence technology is constantly improving. Up to now, China Internet companies such as Baidu, Huawei, Tencent, Ali, JD.COM and 360 have deployed generative artificial intelligence services. The rapid development of technology has put forward higher requirements for regulators and business ecology, and also brought greater challenges.

　　According to industry insiders, the publication of the "Draft for Comment" means that the pace of standardization in the AI industry is accelerating. While delineating the boundaries, it also leaves ample room for development and is committed to avoiding the dilemma of "pollution first and then governance". With more applications landing, some potential risks will be recognized and exposed, and the regulatory measures will be more "symptomatic". The Draft for Comment is only the first step.

Zhang Xinghua

Cctv newsZhang Xinghua, born in 1988, is now the assistant to the squadron leader of the First Squadron of Dongchuan Brigade of Xining Public Security Fire Brigade. Since the police, he has been rated as an advanced individual in Yushu earthquake relief of the Fire Department of the Ministry of Public Security, and won the third-class merit twice. He is like a screw that never loosens, always escorting the property safety of the people.

Dedicate yourself to the police camp.

Zhang Xinghua was born in an ordinary peasant family. Joining the army was his childhood dream and his greatest wish since then. Since the day he became a soldier, he has the expectation of his hometown elders and is determined to make a career in the army.

Since joining the army, he has to get up half an hour earlier than others every morning, cleaning and doing chores. He has done everything in an orderly way and left his shadow in every corner of the army camp.

During his tenure as an assistant to the squadron leader, he insisted on training, working and studying with the soldiers, and often used his rest time to have heart-to-heart talks with other comrades, to understand the soldiers’ family life, personal hobbies, plans to come to the army, etc., and to accurately understand the ideological pulse of the whole team at any time.

Give up one’s life and forget one’s death.

At 2 pm on October 16th, 2012, a thrilling scene happened on the fifth floor of Building 7, Qingyiyuan Community, Xiadu Street, Chengdong District, Xining City. A man was sitting in the fifth floor window with his one-year-old daughter in his arms because of a family dispute, threatening to jump off the building and commit suicide. He was so excited that he could jump at any time.

At the critical moment, Zhang Xinghua jumped down from the sixth floor, pushed the man into the house with a precise foot, and then quickly entered the house from the window to control him. After this video was exposed on the Internet, it was quickly reprinted by many websites, and the reputation of Xining Fire Fighting "Flying Brother" spread like wildfire.

Train hard, devote yourself to fire fighting and strive for honor

In view of the actual situation of the squadron, Zhang Xinghua made careful preparations and scientific training, rationally arranged the training time and progress, carried out training in various forms, increased ideological education and publicity of tournament competition, popularized advanced training experience and practices, and solved the training problems. He knew how heavy the burden was on his shoulders. When the leader asked him if he could carry two burdens on one shoulder, his answer was only hit the floor’s words: "Ensure to complete the task!"

In participating in the 100-meter attack skill project, Zhang Xinghua quickly completed every small movement with the accumulated experience of long-term training, refined and beautifully transported the last bottle, and with super physical strength and tenacious perseverance, he successfully completed the competition project with a good score of 1 minute and 19 seconds. It has achieved the first good result in this subject in the province, adding a heavy sum to the group points of the squadron.

Under his leadership, the squadron stood out among the 34 participating teams, and the double trunk water supply exercise won the first place in the province and finally won the third place in the group, making a historic breakthrough.

Rescue, no regrets, youth casting police soul.

During the "April 14th" Yushu earthquake in 2010, Zhang Xinghua rushed to Yushu Tibetan Autonomous Prefecture in Qinghai Province to participate in earthquake relief under the unified mobilization of the Provincial Fire Corps. During the 72 hours of gold rescue, Zhang Xinghua worked closely with his squadron comrades to fight day and night, excavating 11 victims and saving about 400,000 yuan of people’s property.

During the flood control and flood fighting in Golmud in July, 2010, Zhang Xinghua was brave and tenacious, charging ahead, risking his life again and again with his comrades, charging at the forefront of flood fighting and rescue, braving wind and rain, coping with floods, building dams, fighting disasters and rescuing on water, and building a series of safety dams. He transported sand and gravel with his comrades-in-arms. When there were not enough people to fill the sand and gravel, he simply bandaged his finger when compiling the barbed wire and continued to work. In this harsh climate and difficult conditions, he fought for seven days in a row and blocked the breach dam with his comrades-in-arms for more than 700 meters.

In the past 10 years, Zhang Xinghua has successively completed more than 680 rescues such as Yushu earthquake relief, Golmud flood control, Zhouqu mudslide in Gansu, and 4.9 textile building fire, rescued and evacuated more than 360 people trapped, and saved more than 35 million yuan in economic losses for the country and people. He explained a soldier’s devotion to fire fighting with practical actions. (Source: Ministry of Public Security)

　　Beijing, May 8 (Reporter Xie Qing) Future Network (www.k618.cn Central News Website) Among all parts, the engine is the heart of the plane. Among nearly a thousand engine blades, it is crucial to master the precision grinding technology of blades.

　　As a first-line industrial worker, Hong Jiaguang, the chief technician of China Hangfa Shenyang Liming Aeroengine Co., Ltd., led the team to overcome difficulties and finally mastered the core technology, and won the second prize of National Science and Technology Progress Award.

　　Hong Jiaguang won the National May 1 Labor Medal on the International Labor Day just past. He said to himself, "This is a different Labor Day", which is the highest honor awarded to industrial workers and feels both glorious and great. "

　　This year’s "May 1 International Labor Day", Hong Jiaguang came to Beijing to participate in the 2018 celebration of the "May 1 International Labor Day" and the "Being a Good Master-Building a New Era" Labor and Skills Competition Promotion Conference, and won the National May 1 Labor Medal and made a speech. At the same time, as an award guest, he participated in the award ceremony of "The Most Beautiful Workers in China".

　　After attending two important activities, Hong Jiaguang told reporters that he would immediately return to work overtime. Since joining the work in 1998, Hong Jiaguang has become the chief skill expert of China Hangfa Group, enjoying special allowance from the State Council, and has 6 national inventions and new utility patents.

　　Under the responsibility of "Made in China 2025", Hong Jiaguang took the lead in challenging the "crown jewel" on aero-engines.

　　The so-called "jewel in the crown" refers to aero-engines. For a long time, the precision grinding technology of engine blade roller has always been in a bottleneck state, so how to break through the manufacturing technology of high-precision ultra-thick diamond roller for blade grinding is particularly critical.

　　In this regard, Hong Jiaguang took the initiative to lead the team to overcome difficulties. After more than five years and more than 1,500 attempts, Hong Jiaguang’s team developed a mature precision grinding technology for aero-engine blade rollers, laying a solid foundation for numerical control manufacturing and mass production.

　　The breakthrough of this technology made Hong Jiaguang win the second prize of national scientific and technological progress. As a front-line worker, it is not easy to win this award. Hong Jiaguang said that due to the limitation of knowledge accumulation, he should make special efforts to study technological innovation.

　　On the first-line production line, what defects will be encountered in the actual production of products, Hong Jiaguang should record them at the first time. Then, we need to concentrate on our work, overcome the theoretical weakness and research difficulties, and continue to experiment, so as to gradually make up for our shortcomings.

　　Using a lot of spare time in study, Hong Jiaguang often didn’t go to bed until midnight, just to constantly learn and supplement his professional knowledge. He taught himself the aerodynamics of the engine, stepped into the hall of professional knowledge from the layman, and consulted experts and scholars to constantly overcome difficulties.

　　Just when receiving the second prize of National Science and Technology Progress Award, some experts were surprised that Hong Jiaguang was a first-line industrial worker. In this regard, Hong Jiaguang said that in the work, we must learn more and learn from each other’s strengths. Without continuous learning, we can discover our own shortcomings and the strengths of others, find out the shortcomings in technology and skills, and learn excellent skills. "I think only by doing this can I grow from an ordinary worker to a real great country craftsman."

　　When his technology and skills were improved to a certain extent, Hong Jiaguang found that he would notice many areas that needed improvement in his work. "Explore more and pay more attention to some areas that need improvement, try small inventions, innovations and transformations, and better improve your production efficiency and quality."

　　In this way, Hong Jiaguang mentioned that he can also gradually cultivate and build his own ability and interest in innovation and creation.

　　The new era needs the strength of the team, which makes the workers who are used to working hard try to change. In this regard, Hong Jiaguang is leading the technical team to cooperate with each other and overcome difficulties in unity.

　　After nearly 30 years’ experience in the first-line industry, Hong Jiaguang went from an entry-level lathe worker to a technical expert, and then to a great country craftsman. Seeing the growing number of young industrial workers, Hong Jiaguang also said, "I hope that young people will study more, learn technology seriously, do their work in a down-to-earth manner, and at the same time constantly cultivate their sense of innovation, and combine technology and methods to get exercise and promotion in their posts."

　　Integrating personal ideals into the Chinese dream, Hong Jiaguang deeply stated that young people should be innovative and energetic, and contribute and work hard for the Chinese dream. "Accumulate from the contribution and development of Didi, make yourself grow and contribute to the strength of young people. Guard the heart of the plane and let our Hawk fly higher. "

　　Cctv news(Reporter Zhang Ke): On February 18th, National Medical Products Administration issued an announcement in official website to revise the instructions of Liuwei Dihuang preparation. The announcement pointed out that according to the response evaluation results of adverse drug reactions, in order to further ensure the public’s drug safety, the instructions [Adverse Reactions] [Taboos] and [Precautions] of Liuwei Dihuang preparations (including pills, capsules, tablets, mixtures, decoctions and granules) were uniformly revised.

　　The instructions of Liuwei Dihuang preparation are revised for prescription drugs and over-the-counter drugs respectively. It is pointed out in the revision requirements of OTC drug instructions that [adverse reactions] should include: reports of adverse reactions such as diarrhea, abdominal pain, abdominal distension, nausea, vomiting, gastrointestinal discomfort, loss of appetite, constipation, itching, rash, headache, palpitation and allergy. In the modification requirements of items [Taboo] and [Precautions], the drug safety of allergic people is mentioned.

　　As one of the classic prescriptions of traditional Chinese medicine, Liuwei Dihuang Pill is well known to the public for its effects of nourishing yin and tonifying kidney, and was once called "essential tonic for families". How to eat this kind of "tonic", can it be eaten for a long time, and which people should not take it? CCTV reporter interviewed Yang Liping, the chief pharmacist of Beijing Hospital, to answer your questions.

　　The origin of "tonic medicine"

　　Liuwei Dihuang Pill is composed of six kinds of traditional Chinese medicines, namely Radix Rehmanniae Preparata, Fructus Evodiae, Cortex Moutan, Rhizoma Dioscoreae, Poria and Alismatis Rhizoma. It is characterized by "three tonics and three diarrhea" and mainly tonics. Yang Liping explained that the "three tonics" consist of Radix Rehmanniae Preparata, Fructus Corni and Rhizoma Dioscoreae to tonify liver yin, spleen yin and kidney yin respectively; "Three diarrhea" consists of three herbs, namely Cortex Moutan, Poria and Alisma orientalis, to purge liver heat, spleen dampness and kidney dampness. Among them, the dosage of tonic is heavier than laxative, so tonic is the main one; Liver, spleen and kidney are supplemented with three yin, and the dosage of Radix Rehmanniae Preparata for tonifying kidney yin is the sum of Cornus officinalis and Dioscorea opposita, so tonifying kidney yin is the main method. Therefore, Liuwei Dihuang Pill mainly has the function of nourishing kidney yin and is suitable for patients with kidney yin deficiency.

　　The prescription of Liuwei Dihuang Pill was formed by Qian Yi in Song Dynasty after subtracting two kinds of drugs from Shenqi Pill written by Zhang Zhongjing, a medical sage in the Eastern Han Dynasty, which changed the original medicine for warming kidney-yang into a medicine for nourishing kidney-yin. Its original intention is to treat children with congenital deficiency and stunted five-delay syndrome, that is, "the kidney is afraid of losing its voice, the mouth is incompatible, the spirit is insufficient, the eyes are white, and the face is white". Since then, Liuwei Dihuang Pill has gradually become the ancestor of nourishing yin and tonifying kidney. Modern physicians mainly use Liuwei Dihuang Pill to treat dizziness, tinnitus, soreness of waist and knees, hot flashes due to bone steaming, night sweats and nocturnal emission, thirst-quenching, tinnitus and deafness, hand and foot fever, dry mouth and throat, tooth shaking, heel pain, dribbling urine, and improper opening of the mouth in children.

　　Improper use or "the more you make up, the more empty you become"

　　Yang Liping said that it is unnecessary for healthy people to take Liuwei Dihuang Pill if they have no obvious symptoms of kidney yin deficiency, and they should not take it for a long time.

　　For people with obvious symptoms of kidney-yang deficiency, symptoms such as soreness and coldness of waist and knees, preference for warmth and fear of cold have already appeared, and it is not recommended to take Liuwei Dihuang Pill to avoid aggravating the condition. Many people regard Liuwei Dihuang Pill as a "secret recipe for tonifying kidney" or use it for daily health care for a long time, which is easy to "replenish more and more deficiency", some symptoms are getting worse and worse, and even gastrointestinal problems may occur.

　　Experts pointed out that if you want to know whether you can use Liuwei Dihuang Pills, you must first judge whether you are yin deficiency. You can first look at your tongue, such as red tongue and frequent dry mouth. See if there are often symptoms such as hot flashes, night sweats, insomnia, dizziness, and soreness of the waist and knees; Conditional can see the pulse, whether the pulse is thin and fast. With these signs and symptoms of kidney yin deficiency, Liuwei Dihuang Pill can be used. Even if it is suitable for eating, you should quit smoking and drinking and eat less irritating food.

　　Liuwei Dihuang Pill should be used with caution in patients with cold.

　　Compared with the previous instructions of Liuwei Dihuang Pill, the description of drug use for patients with cold has been changed from "It is not advisable to take cold medicine during taking medicine" in the original [contraindications] to "Use it with caution for patients with cold" in the [Precautions]. Yang Liping said that according to the theory of traditional Chinese medicine, Liuwei Dihuang preparation is too greasy and easy to retain exogenous pathogens, which violates the cold treatment principle of relieving exterior symptoms and dispelling pathogens. The key to cold treatment lies in opening pores, sweating and dissipating heat. However, the function of Liuwei Dihuang preparation is mainly to "harvest", which runs counter to the idea and direction of cold treatment in traditional Chinese medicine.

　　Therefore, people should stop taking Liuwei Dihuang Pill even if they have kidney yin deficiency during the cold stage, and then use it after the symptoms of exogenous diseases are relieved.

　　Who else should not take Liuwei Dihuang Pills? Yang Liping said that Chinese medicine treatment needs syndrome differentiation, and "syndrome differentiation first distinguishes yin and yang". For example, kidney deficiency syndrome can be divided into kidney yin deficiency and kidney yang deficiency. People with kidney-yin deficiency can show symptoms of lack of body fluids, such as dry mouth and mouth, dry skin, soreness of waist and knees, emaciation, hot flashes, red cheekbones, tinnitus, night sweats, red tongue with little coating, and weak and rapid pulse. People with kidney-yang deficiency are afraid of cold, and their hands and feet are cold; Frequent urination, long and clear urine, thin stool, pale and tender tongue, and slow pulse. Symptoms are completely different from kidney yin deficiency, so people with kidney yang deficiency should not take Liuwei Dihuang pills. Because Liuwei Dihuang Pill not only does not tonify kidney-yang, but also consumes kidney-yang, the symptoms of kidney-yang deficiency in patients will be aggravated after use.

　　In addition, people with kidney yin deficiency but poor spleen and stomach function have symptoms such as weakness of spleen and stomach, indigestion, chest tightness, anorexia, abdominal distension in loose stool, thick tongue coating, and excessive phlegm and dampness, and should not take it. Because the rehmannia glutinosa and Cornus officinalis in Liuwei Dihuang Pill are too greasy, it will hinder the digestive function after taking it, and may also aggravate the symptoms of loose stool, so it is not recommended to take it.

　　Also, healthy people don’t need to take it. Although Liuwei Dihuang Pill has the function of tonifying kidney, healthy people who have no obvious symptoms of kidney yin deficiency may not have any side effects in the short term, but long-term use may cause discomfort such as fullness, loose stool and loss of appetite.

　　Finally, note that Liuwei Dihuang Pill cannot be taken with rifampicin. Because Cornus officinalis contains a lot of organic acids, it will increase the toxicity of rifampicin to the kidney. (Proofread by Chen Yanhui)

　　On March 28th, 2023, local time in Seoul, South Korea, Ren Zhuyuan, spokesman of the Korean Foreign Ministry, answered questions about the examination and approval results of Japanese government primary school textbooks. Vision china diagram

　　On March 28th, local time, the South Korean Foreign Ministry summoned the Japanese general minister to lodge a solemn protest against the Japanese government’s approval of textbooks containing "improper claims". The South Korean side pointed out that these textbooks "distorted history" and played down the crimes committed during the Japanese aggression. At the same time, they advocated Japan’s sovereignty over Dokdo (called Zhudao in Japan). The South Korean side deeply regretted it and asked Japan to correct it.

　　Japan’s Ministry of Education, Culture, Sports, Science and Technology announced earlier that day that 149 primary school textbooks had been approved and will be used in the 2024 school year.

　　After analyzing the sample books, Yonhap News Agency found that the Japanese side played down what it did during its colonial rule of the Korean Peninsula from 1910 to 1945 in the new textbooks. For example, when describing Koreans who were forcibly recruited into the army, the new textbook changed to the word "joining the army", which is consistent with the Japanese claim that these people "voluntarily" joined the army.

　　In another textbook, Japan called Zhudao its inherent territory, which was illegally occupied by South Korea at this stage.

　　This island is located in the eastern waters of the Korean peninsula, covering an area of about 0.18 square kilometers. South Korea, North Korea and Japan all claim sovereignty over it. At present, the island is actually controlled by South Korea.

　　In addition, the South Korean side also pointed out that the new Japanese textbooks downplayed the relevant expressions of forced labor during World War II.

　　On the 28th, Zhao Xiandong, the first official of the South Korean Foreign Ministry, summoned Naoki Kumatani, the Japanese ambassador to South Korea, to protest against the Japanese practice. According to South Korean media, due to the temporary return of Japanese ambassador to South Korea Xiang Xing Koichi, the South Korean side summoned Naoki Kumatani as the temporary charge d ‘affaires instead. On-site photos show that Naoki Kumatani walked into the South Korean Foreign Ministry building in Seoul with a serious expression.

　　South Korean Foreign Ministry spokeswoman Lin Zhu Yong said in a statement that Japan’s claim to have sovereignty over Dokdo is "unreasonable" and unacceptable. South Korea deeply regrets and urges Japan to show sincerity and correct the problem.

　　An official of the South Korean Foreign Ministry said that although relations between South Korea and Japan have improved recently, territorial disputes, textbooks and "comfort women" between the two countries have not been resolved, and this has not changed. The ROK will continue to communicate with the Japanese side through diplomatic channels and demand that the textbook issue be corrected.

　　In response to the request of the ROK, the Japanese side has not responded.

　　This is not the first time that a "textbook storm" has occurred in Korea and Japan. In April, 2021, the Ministry of Education, Culture, Sports, Science and Technology of Japan approved the application of five publishing houses to modify or delete the related expressions of "comfort women" in textbooks, and agreed to change "comfort women with the army" into "comfort women" and "forced removal" into "forced mobilization" or "expropriation" in an attempt to wash away the Japanese war crimes. The South Korean Foreign Ministry deeply regrets this and urges Japan to show its sincerity in solving historical problems between the two countries.

　　Medical technicians in Cihu High-tech Zone, Ma ‘anshan City, Anhui Province are developing COVID-19 pharmaceutical core intermediates. Wang Wensheng photo/bright picture

　　Workers of a pharmaceutical company in Shijiazhuang, Hebei Province work in the pharmaceutical production workshop. Xinhua news agency

　　　 [Endeavour, New Journey, New Era, Great Change]

　　　 Since the reform of evaluation in 2015, National Medical Products Administration has approved 95 innovative drugs and approved 155 innovative medical devices to be listed.

　　　 Five Covid-19 vaccines were approved for conditional marketing, two Covid-19 vaccines were approved for emergency use, and 34 vaccine varieties with five technical routes entered clinical trials.

　　　 106 novel coronavirus detection reagents were approved, including 38 nucleic acid detection reagents, 37 antibody detection reagents and 31 antigen detection reagents.

　　　 "The quality of registration application materials is not high, and it needs to be supplemented and improved many times during the review process, which seriously affects the efficiency of review and approval; Repeated construction and application of generic drugs, vicious competition in the market, and the quality of some generic drugs is far from the international advanced level; The listing approval time of new drugs urgently needed in clinic is too long, and drug research and development institutions and researchers cannot apply for drug registration, which affects the enthusiasm of drug innovation. "

　　　 This is a frank and incisive analysis of drugs and medical devices related to people’s lives and health in a the State Council document seven years ago. This analysis resonates with the confusion of the people: Why are some drugs "slower" to market in China than in foreign countries? Why do some people go overseas to purchase medicines?

　　　 The full name of the the State Council document is Opinions on Reforming the Examination and Approval System of Medicines and Medical Devices, which was issued in August 2015, thus kicking off the reform of the examination and approval system of medicines and medical devices in China (hereinafter referred to as the examination and approval reform). Especially since its establishment in 2018, National Medical Products Administration has continuously deepened the reform of evaluation, encouraged the innovation of drugs and medical devices, improved the quality of drugs and medical devices, increased effective supply, and effectively guaranteed people’s health and life safety.

1. The backlog of registration applications has been solved.

　　　 The quality of drugs and medical devices is related to everyone’s health and safety, which is the original intention of implementing the review and approval system. However, if the evaluation efficiency is too low, it will lead to the lag of product listing time, which will also affect people’s health and safety. After all, disease waits for no one.

　　　 Take drugs as an example. In the past, the backlog of drug registration applications in China was serious, with a maximum of 22,000 applications. Many drugs have to wait several years for approval after they apply for registration. Pharmaceutical companies are helpless and patients are miserable.

　　　 How to speed up the review? This is the first problem to be solved in the reform. The drug regulatory authorities, seeing the move, launched a series of powerful measures — —

　　　 Full implementation of the implied license system for 60-day expiration of drug clinical trials, which is one-third shorter than the 90-day review time limit before the reform.

　　　 We will establish and improve the procedures for accelerating the listing and registration of drugs, optimize the review and approval process, and give priority to the clinical shortage of drugs, anticancer drugs, drugs for children, drugs for rare diseases, drugs for major infectious diseases, vaccines urgently needed for disease prevention and control, and innovative high-end medical devices, thus greatly shortening the review time limit.

　　　 Drugs that show efficacy in early clinical trials can be conditionally approved for marketing and used in urgent need patients who can’t wait any longer.

　　　 … … … …

　　　 As a drug technical evaluation institution, National Medical Products Administration Drug Evaluation Center has also strengthened the management of evaluation items, refined the evaluation sequence, strengthened the management of time limit, set up special groups, increased reviewers, revised the evaluation points, standardized technical requirements, etc., and the evaluation standards, quality and efficiency of drugs have been greatly improved.

　　　 "From the peak in 2015, there was a backlog of more than 20,000 applications. By 2018, more than 90% of them were reviewed within the time limit, and China’s drug review and approval entered the fast lane." The relevant person in charge of the Department of Drug Registration of National Medical Products Administration told the reporter that, for example, in terms of new drugs urgently needed overseas, by the end of 2021, 51 new drugs urgently needed overseas were approved for listing, among which the review of rare diseases drugs was completed within 3 months, and the review of other drugs urgently needed clinically was completed within 6 months, which greatly shortened the time for listing new drugs urgently needed overseas in China.

2. The innovation enthusiasm of the pharmaceutical industry has been stimulated.

　　　 The backlog of applications has been solved, and the speed of drug listing has been accelerated. However, in order to meet the people’s drug demand, new drugs need to be put on the market continuously. Encouraging drug innovation is the core of evaluation reform.

　　　 In 2015, the Opinions on Reforming the Examination and Approval System of Drugs and Medical Devices raised the standards for drug approval, and changed the new drugs from "drugs that were not marketed in China" to "drugs that were not marketed in China or abroad", that is, "global new". Two years later, the General Offices of the General Office of the Central Committee of the CPC and the State Council issued the Opinions on Deepening the Reform of Review and Approval System and Encouraging the Innovation of Pharmaceutical and Medical Devices, and made special arrangements for the innovation of pharmaceutical and medical devices.

　　　 The reporter learned that in order to encourage the research and development of innovative drugs and medical devices, National Medical Products Administration not only gave support in priority evaluation, but also formulated a series of technical guiding principles, such as "Technical Requirements for Application for Pharmaceutical Common Problems in Phase I Clinical Trials of Innovative Chemicals", to guide the application for research and development of innovative products. Reviewers will also take the initiative to communicate with R&D producers in key review links such as pre-clinical, clinical and pre-listing, so as to avoid detours.

　　　 "The review reform encourages clinical value-oriented drug innovation, optimizes the review and approval procedures for innovative drugs, and accelerates the review of innovative drugs that are urgently needed in clinic, which greatly stimulates the research and development vitality of pharmaceutical companies." The relevant person in charge of Renfu Pharmaceutical Group Co., Ltd. told reporters that in recent years, a number of new drugs have been approved for listing in this enterprise, and new breakthroughs have been achieved in innovation capability.

　　　 Among many reform measures, the system of drug marketing license holders deserves attention. Previously, only pharmaceutical manufacturers could apply for drug registration. In order to register drugs, researchers and research institutions must first invest and build factories themselves. This management system of product registration and production license is not conducive to drug innovation. In 2015, China launched a pilot system of drug marketing license holders in 10 provinces and cities, and drug research and development institutions and researchers can apply for registered drugs. Expert analysis pointed out that this move reduced the capital investment and time cost of drug developers, and new drugs could be listed three to five years in advance. In 2019, the drug marketing license holder system was written into the newly revised drug administration law and was fully implemented nationwide.

　　　 According to National Medical Products Administration, in recent years, China has made great progress in the development of innovative drugs. From 2018 to 2021, the number of innovative drugs approved for marketing increased year by year, with 11, 12, 20 and 45, respectively, including Covid-19 vaccines and clinically urgent therapeutic drugs in the fields of tumors, immune system diseases and rare diseases. The pace of medical device innovation is also accelerating. In 2021, 35 innovative medical devices were approved for listing, which is the largest number of innovative products approved in recent years.

3. Consistency evaluation improves the efficacy of generic drugs.

　　　 In recent years, many drugs that were originally expensive began to reduce their prices. Careful observation shows that there is a "hero" behind the decline in drug prices — — Generic drugs.

　　　 Innovative drugs provide new options for treating diseases and saving lives, but for the vast majority of patients, generic drugs are their life. According to National Medical Products Administration, China’s modern pharmaceutical industry started late, and the production of drugs is mainly imitation. More than 95% of the chemicals that have been approved for marketing are generic drugs.

　　　 Generic drugs are imitations of the original drug after the patent protection period expires, and the price is much lower than that of the original drug. In the past, China’s generic drug evaluation and approval standards were not high, and there was a lack of high-quality generic drugs, and the curative effect was very different from that of the original drug.

　　　 Improving the quality and efficacy of generic drugs is an important goal of evaluation reform, and the solution is the consistency evaluation of generic drug quality and efficacy — — For generic drugs that have been approved for marketing, the evaluation should be carried out according to the principle of consistency with the quality and efficacy of the original drug. The core is that generic drugs should reach the level consistent with the original drug in quality and efficacy, and can replace the original drug in clinic.

　　　 "There are several key issues in carrying out consistency evaluation, one is the selection and determination of reference preparations, the other is the determination of technical standards, and the third is to strictly follow the procedures." According to the person in charge of National Medical Products Administration, the Bureau ensured the smooth development of generic drug conformity evaluation by improving the evaluation system, strictly evaluating standards, strengthening service guidance and optimizing the workflow. At present, 4677 specifications of generic reference preparations have been published, and 2044 specifications and 437 varieties have been applied for through consistency evaluation.

　　　 Consistency evaluation puts generic drugs on the right track, and ultimately benefits the people. Since the pilot of centralized drug procurement and use organized by the state was launched nationwide in 2019, a number of domestic generic drugs won the bid. Medical insurance, health insurance and other departments have organized medical institutions to carry out research on 14 representative generic drugs that won the bid, and confirmed that these 14 generic drugs that passed the consistency evaluation are clinically equivalent to the original drugs. Generic drugs with the same efficacy as the original drug are not only cheaper, but also further reduce the price of the original drug under competitive pressure, greatly reducing the burden of patients.

4, emergency review and approval for epidemic prevention and control to provide a strong guarantee.

　　　 4 days, which is the time for China to complete the review and approval of the first Covid-19 nucleic acid detection reagent and sequencing reagent in the world.

　　　 On January 20, 2020, National Medical Products Administration Instrument Center started the emergency work overnight, and the reviewers stayed up all night to connect with the enterprises one by one, and the review and research and development were carried out simultaneously. On January 26th, the first batch of four in vitro diagnostic reagent products were approved for marketing, which provided an effective detection method for the first line of anti-epidemic.

　　　 The outbreak of epidemic situation in COVID-19 challenges the evaluation reform. Xu Jinghe, deputy director of National Medical Products Administration, said at the Boao Forum for Asia in 2021 that the role of drug supervision departments in epidemic prevention and control has changed, from reviewers to instructors, working with enterprises to speed up product listing.

　　　 It is understood that National Medical Products Administration made every effort to carry out emergency review and approval during the epidemic. Five Covid-19 vaccines have been approved for conditional marketing, two Covid-19 vaccines have been approved for emergency use, and 34 vaccine varieties from five technical routes have entered clinical trials. Organized the formulation of three technical guidelines for research and development of therapeutic drugs in Covid-19, approved 58 applications for clinical trials of therapeutic drugs in Covid-19, and approved the registration and listing of Qingfei Detoxification Granules, Huashi Detoxification Granules and Xuanfei Detoxification Granules. 106 novel coronavirus detection reagents were approved to effectively meet the needs of epidemic prevention and control.

　　　 The epidemic is not over yet, and the emergency review and approval is still going on. As long as people’s health needs it, the evaluation reform will not stop. The drug supervision departments and reviewers have been speeding up on the road of realizing healthy China, so as to run out of acceleration for people’s health.

　　　 (Reporter Chen Haibo)

Cctv newsOn June 16th, at the press conference of the National Development and Reform Commission in June, some media asked: This year, the demand for electricity in China has grown steadily and rapidly, especially in the recent summer when the peak of electricity consumption is coming. What is the preparation for the peak of electricity in summer? What measures will the National Development and Reform Commission take to ensure the smooth operation of electricity this summer?

In this regard, Meng Wei, spokesperson of the National Development and Reform Commission, said that since the beginning of this year, the National Development and Reform Commission has focused on the safe and stable supply of energy and electricity, and continued to strengthen the construction of an energy production, supply, storage and sales system. Judging from the current situation, the installed capacity of power generation in China has continued to grow steadily, and the coal storage of power plants has reached a record high of 187 million tons, which has a solid foundation for ensuring power supply during the peak summer this year.

On June 14th, the National Development and Reform Commission held a video conference to specially deploy the national energy peak summer work in 2023. In the next step, we will give full play to the role of the inter-ministerial coordination mechanism of coal, electricity, oil and gas transportation support, compact the main responsibility of local and enterprise energy supply, and focus on five aspects.

First, promote the construction of various power projects. Adhere to the "national chess game", systematically plan and promote the construction of various power sources such as supporting power sources and new energy sources, strengthen the construction of power grids, and do a good job of connecting power to the grid to ensure that all inputs should be made before the peak summer this year.

The second is to strengthen fuel supply security. We will continue to organize the production and supply of coal and natural gas, and urge all localities and power generation enterprises to keep the coal stored in power plants at a high level, so as to ensure the high calorific value coal, gas, electricity and hydropower energy storage required for peak power generation.

The third is to promote all kinds of generator sets to be fully developed. Ensure that the output level of thermal power during peak hours is better than normal, optimize the operation of reservoir groups, improve the peak power generation capacity of hydropower, and promote the multi-use of wind power, solar power and nuclear power.

Fourth, do a good job in optimal dispatching of national power grid operation. Give full play to the advantages of large power grid resource allocation, strengthen national overall planning, strengthen cross-network mutual assistance, make full use of inter-provincial and inter-regional transmission channels, and do a good job in power supply guarantee in key areas and important time periods.

Fifth, do a good job in power demand side management. Adhere to both open source and throttling, guide local governments to better play the role of economic means to adjust, actively guide users to independently optimize and adjust power demand, promote the balance between power supply and demand, and effectively ensure the safety and stability of people’s livelihood and key power consumption.

　　Xinhua News Agency, Beijing, August 30th-The Ministry of Water Resources issued a circular on the 30th, predicting that autumn rains in West China are obvious in the near future and autumn, and autumn floods may occur in Jialing River, Minjiang River, Tuojiang River, Hanjiang River and Weihe River in the Yangtze River basin.

　　At the same time, the circular shows that regional storms and floods may occur in coastal areas of South China, and autumn droughts may occur in central Jiangnan and eastern South China. Flood and drought disaster prevention is facing severe challenges.

　　Li Guoying, deputy commander of the National Defense General and Minister of Water Resources, presided over a meeting on the same day to analyze and judge the current and autumn flood and drought situation and arrange key work for flood and drought disaster prevention.

　　Li Guoying demanded that we should do a good job in autumn flood prevention in key river basins, and conduct research and analysis on reservoir by reservoir. While scientifically intercepting floods and ensuring flood control safety, we should seize the favorable opportunity at the end of flood season to reserve water resources and create conditions for ensuring the safety of urban and rural water supply in autumn and winter this year and even next spring.

　　At the same time, Li Guoying stressed that it is necessary to do a good job in drought prevention in the Pearl River and Hanjiang River basins in advance, effectively carry out the storage and dispatching of key reservoirs in the upper reaches of the Xijiang River, especially the Datengxia Hub in the main stream of the Xijiang River, and provide water resources guarantee for ensuring the water supply safety in cities such as Macao and Zhuhai.

　　At present, the battle for talents in various places is in full swing, and top talents are even more "fragrant". Hospitals are no exception. Last week, the provincial people’s doctor introduced three academicians a week, which attracted the industry’s surprise. During the interview, the reporter learned that the introduction of flexible talents has been surging in Nanjing. Many 3A hospitals have introduced academician workstations, and the First Hospital of Nanjing has invited top national cardiac surgeons to perform 150 operations in three months …

　　Love Nanjing Nanjing Morning Post reporter Qi Zaibing Sun Sujing

　　Save people’s doctors and introduce three academicians a week

　　From June 23rd to June 27th, the third batch of flexible high-end talents from jiangsu province hospital signed a contract in this hospital. Academician Ning Guang of Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Academician Yu Jinming of Shandong Cancer Hospital, Academician Ge Junbo of Zhongshan Hospital affiliated to Fudan University, Professor Qin Shukui of Bayi Hospital of the People’s Liberation Army, and Professor Li Jin of Oriental Hospital affiliated to Tongji University signed an employment agreement with the hospital, officially becoming a special medical expert in the hospital and signing a contract to become distinguished professor of South Medical University; And the "Academician Workstation" led by two academicians, Yu Jinming and Ge Junbo, also settled in the hospital. So far, the hospital has introduced 12 domestic and foreign high-end medical talents in three batches to settle down flexibly in the province, which has become a new attempt for the hospital to introduce top talents.

　　It is understood that in the past two years, The hospital has signed talent introduction agreements with many experts, such as Professor Jiang Zefei from the 307th Hospital of the Chinese People’s Liberation Army, Professor Ji Jiafu from Peking University Cancer Hospital, Professor Zhou Pinghong from Zhongshan Hospital affiliated to Fudan University, Professor Huo Yong from the First Hospital of Peking University, Professor Xuanyuan Qingshi, Director of HiPep Institute in Japan, Professor Liang Hanguang, Director of Surgery of Seoul National University, and Academician Li Zhaoshen, Director of Gastroenterology Department of Changhai Hospital affiliated to the Second Military Medical University. Together with the five distinguished professor introduced this time, 12 top talents have settled in the hospital, involving oncology.

　　"First-class centers call for first-class talents, and first-class talents look forward to a first-class platform. I believe that signing experts can also play their greater value in jiangsu province hospital, a high-level platform." Dean Tang Jinhai of jiangsu province hospital said that the hospital attaches great importance to internationalization, intelligence and talent superiority, and the introduction of flexible talents will quickly help the hospital master advanced medical technology, enhance its service capacity and benefit the people.

　　Three academicians of Gulou Hospital have been quietly "working" for two years.

　　It is understood that in the introduction of academicians, Nanjing Gulou Hospital is also a big deal. As early as two years ago, Gulou Hospital took the lead in introducing the academician workstation model, and now three academicians have quietly "worked" for two years.

　　Dai Yutian, director of the Science and Technology Department of Nanjing Gulou Hospital, introduced that in 2016, the hospital signed contracts with academicians Ning Guang, Liu Zhihong and Qiu Guixing respectively to establish academician workstations. Among them, Academician Ning Guang, a famous endocrinologist from Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Academician Liu Zhihong from Nanjing General Hospital in urology and Academician Qiu Guixing from Peking Union Medical College Hospital in orthopedics were introduced. Several experts come to Gulou Hospital regularly or send people to listen to the department development and clinical research reports, give clinical and academic guidance, train relevant technical innovation talents, and put forward suggestions and opinions, so as to "find the difference by benchmarking". Dai Yutian introduced that the establishment of the academician workstation has trained talents, improved the clinical and scientific research level of the hospital, and enabled the people to enjoy the quality services of top medical experts at their doorstep.

　　Dai Yutian introduced that under the leadership of the Nanjing Municipal Health Planning Commission, in the next step, Gulou Hospital will continue to build new academician workstations to further enhance the hospital’s talent strength and clinical research level and better serve patients.

　　Dr. Yang from the First Hospital performed 150 operations in three months.

　　Also on May 18th this year, a foreign doctor appeared at the awarding ceremony of Jinling Friendship Award of Nanjing Municipal People’s Government in 2018. Professor Mike Carmack, the chief physician of Cardiovascular Surgery in Nanjing First Hospital (American, MD), was awarded the "Jinling Friendship Award" by Nanjing Mayor Lan Shaomin, becoming one of the ten foreign experts who won this honor in the city.

　　It is understood that Professor Mike Carmack is a famous expert in cardiovascular surgery in the United States. He has been engaged in clinical work of cardiothoracic surgery in the United States for a long time since 1984. He has a very comprehensive cardiac surgery technology, especially in severe heart bypass surgery, complex heart valve surgery, reoperation, aortic surgery (aneurysm and aortic dissection) and heart transplantation. He is "the fifth doctor in the world who has performed total artificial heart implantation" and enjoys a high reputation in the world. As an expert selected by Jiangsu’s "Hundred Talents Program", Professor Mike Camack officially joined the Cardiovascular Surgery Team of the First Hospital on February 22 this year, and signed a three-year employment agreement to become a full-time foreign doctor in the First Hospital.

　　Qin Wei, Ph.D., Cardiovascular Surgery, First Hospital, introduced that Professor Carmack has been fully involved in cardiovascular surgery, undertaking tasks such as expert outpatient service (half a day each week in the headquarters and Hexi Campus), ward rounds, surgical treatment and personnel training. Now, Professor Carmack takes part in the early handover of departments every day, and the handover of departments adopts English communication, which greatly improves the overall English level of departments. Professor Carmack takes part in preoperative discussion every day, making operation plans, watching films with young doctors, participating in clinical decision-making, guiding doctors to operate, etc. In particular, he advocated the concept of rapid postoperative recovery, so that patients can leave the ventilator as soon as possible after surgery, remove the drainage tube and get out of bed as soon as possible, which greatly shortened the hospitalization time.

　　As of May 24th, Professor Carmack has participated in 150 operations, and 91 cases of difficult operations have been performed by him, including two cases of heart transplantation, aortic valve replacement combined with ascending aorta replacement combined with heart bypass, and the second operation for patients after heart surgery. In the past three months, there have been three operations every day on average, and no one has died. Such a low mortality rate is also very rare in the United States.

　　A number of 3A hospitals introduced academician workstations.

　　During the interview, the reporter found that in addition to the Provincial People’s Hospital and the Drum Tower Hospital, a number of top three hospitals in Nanjing constantly "borrowed" from the top technical fields in the country and the world, and invited academicians and Nobel Prize winners to set up workstations.

　　Nanjing Zhongda Hospital also cooperated with Sun Yinghao, an academician of China Academy of Engineering and a national academic leader in urology, to set up an "academician workstation". It is understood that in addition to setting up academician workstations in urology, Zhongda Hospital will also strengthen its strength in surgical disciplines such as cardiothoracic surgery and general surgery by setting up academician workstations. According to the strategic plan of Nanjing No.1 Hospital, the hospital will introduce 8 academicians in recent years, involving oncology, cardiovascular, nuclear medicine and other departments. At present, five academicians, including Han Yaling, Chen Zhinan, Zhan Qimin, Hu Shengshou and Zhong Shizhen, are stationed to guide the work.

　　Graded diagnosis and treatment, big hospitals urgently need top talents.

　　An industry expert said that the "graded diagnosis and treatment" promoted by this round of medical reform has made large and small hospitals more clear about their respective positioning. "Minor illnesses are in the community, and serious illnesses go to the hospital." The top three hospitals are no longer "grasping the eyebrows and beards", but taking on more and more difficult diseases. The requirements for technology are getting higher and higher, so the demand for top medical talents is more urgent. However, the dilemma of long training period and difficult mobility of top doctors also exists objectively. How to win more top doctors for hospitals? Academician workstation has become a feasible mode, which has been paid more and more attention by hospitals and departments.

　　By "marriage" with academicians of the two academies, on the one hand, the hospital flexibly introduces high-level talents, participates in the research of international frontier scientific research projects, and improves the ability to treat difficult and complicated diseases; On the other hand, it is undoubtedly a win-win situation for the hospital to learn from academicians and experts and train a group of academic leaders and key talents, so as to rapidly improve the scientific research and clinical strength of the hospital, further strengthen its own strength and benefit more patients.